Healing & Tissue RepairIn StockHealing & Tissue Repair
TB-500
Also known as: Thymosin Beta-4 fragment, Fequesetide
Synthetic peptide fragment of Thymosin Beta-4 studied in actin-binding, cell-migration, and tissue-remodeling research.
TB-500 is a synthetic peptide corresponding to an active fragment of Thymosin Beta-4 (Tβ4), an endogenous 43-amino-acid actin-binding protein found in most mammalian tissues.
The fragment retains the biologically active LKKTETQ sequence that has been the focus of extensive preclinical investigation.Research on Thymosin Beta-4 and TB-500 spans cytoskeletal biology, actin polymerization dynamics, and models of cell migration relevant to wound repair and angiogenesis.
Published studies have examined these peptides in both cell-culture and animal-model contexts, exploring roles in tissue-remodeling pathways, microRNA-146a modulation, and integrin signaling cascades.TB-500 is frequently paired with BPC-157 in healing-research protocols due to their complementary mechanisms — BPC-157 being more studied in vascular and nitric-oxide signaling, and TB-500 in cytoskeletal and cell-motility research.
Research applications
- Actin polymerization and cytoskeletal organization
- Cell migration and wound-repair models
- Angiogenesis and endothelial biology research
- Collagen deposition and extracellular matrix studies
- Comparative peptide pharmacology alongside BPC-157
Technical profile
- Net content
- 10 mg
- Molecular formula
- C212H350N56O78S
- Molecular weight
- 4963.44 g/mol (full-length Tβ4 fragment)
- CAS
- 77591-33-4
- Sequence
- Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
For research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease. Catalog availability restricted to verified licensed practitioners.
TB-500 is a synthetic fragment of thymosin beta-4, a protein present in virtually all human and animal cells. Research indicates it promotes angiogenesis, cell migration, keratinocyte migration, and collagen deposition for tissue repair.
